Figure 3

Cell densities of retinal microglial cells and hyalocytes. Solid lines are from OIR mice, while dashed lines are from controls without oxygen treatment. Red lines label microglia data from the superficial layer and violet lines label hyalocytes from the peripheral zone, respectively. While microglial cell densities of the peripheral zone were almost constant over time, a marked drop was observed in the deep layer of OIR mice after return to normal air. Activated microglia (yellow line) were found in the superficial layer only and peaked at P10 and at P17. The cell density of hyalocytes decreased over time. Error bars indicate standard errors. Significant differences were found (1) in the deep layer of the central avascular zone in OIR between P12 and P14, (2) in activated microglia in the superficial layer of the central avascular zone between P7 and P10, and (3) between P14 and P17.