Skip to main content

Table 1 Abbreviated gene clusters identified after SCI

From: Delayed inflammatory mRNA and protein expression after spinal cord injury

Gene Name

Description

GenBank Accession

Fold Change

   

4hr

24hr

72hr

7d

14d

28d

3mo

6mo

Group 1: Acute Expression

Ptgs2 (COX-2)

Anchor Mediator of inflammatory functions, enzymatically transforms arachidonic acid into prostaglandins

S67722

2.3*

1.3*

1.7

0.9

0.6

0.9

2.9 *

2.0 *

Osteopontin

Pro-inflammatory cytokine

NM_012881

1.6

5.0*

4.7*

4.6*

0.9

0

1.3

1.7 *

S100a8 (Calgranulin)

Calcium binding protein expressed by monocytes

NM_053822

5.8*

5.5*

2.8*

0.9

0.1

 

1.3

0.9

Group 2: Delayed Expression

C1qB

Anchor Component of the complement chain and binds antigen.

x71127

0.97

2.2*

3.5*

7.1*

5.9 *

7.2 *

2.2 *

1.6 *

Galectin3

Galactose specific lectin that binds IgE and extracellular matrix proteins.

JO2962

1.5*

2.4*

2.3*

10*

4.4 *

12.8*

4.0 *

4.0 *

P22/CYBa

Core component of NADPH Oxidase within phagocytes.

U18729

1.1

1.9*

2.8*

9.3*

7.8 *

4.4 *

1.7 *

1.4

OX44/CD53

Integral membrane protein that mediates signal transduction

M57276

0.9

2.2*

3.5*

6.0*

3.8 *

5.3 *

3.2 *

2.1 *