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Table 1 Distribution of the TLR2 -196 to -174 del polymorphism in LOAD cases and controls.

From: Toll-like receptor 2 -196 to -174 del polymorphism influences the susceptibility of Han Chinese people to Alzheimer's disease

  N Genotypes n (%) Alleles n (%)
   ins/ins del/ins del/del P del ins P
AD 400 150(37.5) 161(40.2) 89(22.2) 0.026 461(57.6) 339(42.4) 0.009
Controls 400 172(43.0) 168(42.0) 60(15.0)   512(64.0) 288(36.0)  
ApoEε4(-)         
AD 260 94(36.2) 104(40.0) 62(23.8) 0.027 292(56.2) 228(43.8) 0.009
Controls 339 144(42.5) 143(42.2) 52(15.3)   431(63.6) 247(36.4)  
ApoEε4(+)         
AD 140 56(40.0) 57(40.7) 27(19.3) 0.526 169(60.4) 111(39.6) 0.251
Controls 61 28(45.9) 25(41.0) 8(13.1)   81(66.4) 41(33.6)  
  1. ApoE ε4 (+): subjects who carry one or two ε4 alleles; ApoE ε4 (-): subjects who do not carry an ε4 allele.