Table 1 Distribution of the TLR2 -196 to -174 del polymorphism in LOAD cases and controls.
N | Genotypes n (%) | Alleles n (%) | ||||||
|---|---|---|---|---|---|---|---|---|
ins/ins | del/ins | del/del | P | del | ins | P | ||
AD | 400 | 150(37.5) | 161(40.2) | 89(22.2) | 0.026 | 461(57.6) | 339(42.4) | 0.009 |
Controls | 400 | 172(43.0) | 168(42.0) | 60(15.0) | 512(64.0) | 288(36.0) | ||
ApoEε4(-) | ||||||||
AD | 260 | 94(36.2) | 104(40.0) | 62(23.8) | 0.027 | 292(56.2) | 228(43.8) | 0.009 |
Controls | 339 | 144(42.5) | 143(42.2) | 52(15.3) | 431(63.6) | 247(36.4) | ||
ApoEε4(+) | ||||||||
AD | 140 | 56(40.0) | 57(40.7) | 27(19.3) | 0.526 | 169(60.4) | 111(39.6) | 0.251 |
Controls | 61 | 28(45.9) | 25(41.0) | 8(13.1) | 81(66.4) | 41(33.6) | ||