Figure 6
From: Soybean-derived Bowman-Birk inhibitor inhibits neurotoxicity of LPS-activated macrophages
Effect of BBI on NMDA-induced neuronal death. Rat cortical neurons were incubated with or without MK801 (5 μM) and/or BBI (100 μg/ml) for 1 h and then treated with LPS- (100 ng/ml) activated macrophage supernatant (LPS/MΦ SN) or NMDA (10 μM) for 24 h. Unactivated donor-matched macrophage supernatant- (MΦ SN) treated cortical neuron cultures were used as controls. Data are expressed as mean ± SD of three independent experiments. (**P < 0.01)