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Table 3 Proliferation of PDGFRα, PDGFRβ, and IBA-1 expressing cells in wild type and NG2 null mice.

From: Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord

  WT KO
Total Pα positive cells 178.23 ± 20.3 127.94 ± 18.4*
Pα/BrdU positive cells 26.4 ± 2.2 10.76 ± 2.9
Mitotic indices 14.81 ± 3.1% 8.41 ± 0.6%**
Total Pβ positive cells 29.8 ± 5.7 21.91 ± 3.4*
Pβ/BrdU positive cells 4.53 ± 0.8 2.31 ± 0.9
Mitotic indices 15.2 ± 0.6% 10.52 ± 0.6%***
Total IBA-1 positive cells 217.94 ± 14.8 74.45 ± 12.3***
IBA1/BrdU positive cells 19.66 ± 3.6 4.71 ± 3.5
Mitotic indices 9.02 ± 1.2% 6.32 ± 1.8%*
  1. Total numbers of PDGFRα (Pα), PDGFRβ (Pβ), and IBA-1 positive cells, along with BrdU incorporation, were determined in 0.1 mm2 areas of the dorsal column at 7 days postsurgery. Mitotic labeling indices for OPCs, pericytes, and macrophages/microglial cells are expressed as the percentage of each cell type that is BrdU positive. Data represent the mean ± S.D. Statistically significant differences between wild type and NG2 null mice are indicated by * < 0.05; ** < 0.01; *** < 0.001.