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Figure 5 | Journal of Neuroinflammation

Figure 5

From: Systemic inflammatory challenges compromise survival after experimental stroke via augmenting brain inflammation, blood- brain barrier damage and brain oedema independently of infarct size

Figure 5

Systemic inflammatory challenges induce neuroinflammatory changes in the brain. A. In homogenates of brain hemispheres, real-time PCR reveals changes in cytokine expression 3 h after intraperitoneal LPS administration or anaphylaxis. Values represent fold changes over control. B. Cytometric bead array shows increased cytokine levels in the brain 3 hours after LPS treatment. C. Elevated cytokine mRNA levels confirm central induction of inflammation after peripheral LPS treatment. Cytokine expression was analysed with real-time PCR in brain hemisphere samples. Data are representative of 3-7 mice in each group. One-way ANOVA followed by Bonferroni's post-hoc comparison (*P < 0.05, **P < 0.01).

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Journal of Neuroinflammation

ISSN: 1742-2094