Figure 3
Functional polarity to GM-CSF in BMEC permeability of HIV-1 (A) and TEER (B). BMECs were exposed to GM-CSF (1, 10, and 100 ng/mL) in the luminal or abluminal chamber for 4 hr. In panel A, results are expressed as % of control. The control values of permeability coefficient for 131I-HIV-1 in panel A was 137 ± 0.13 × 10-5 and 1.32 ± 0.13 × 10-5 cm/min for the luminal and abluminal control, respectively. Values are means ± SEM (n = 3-12). **P < 0.01, significant difference from control.