Figure 7

Expressions of CD69, MHC molecules, CD40, PDL-1, and Foxp3 on CNS cells. Expressions of CD69 and FoxP3 molecules on T cells, and MHC, CD40 and PDL-1 molecules on CD11b⁺ cells in the CNS of mice were determined at 14 and 28 dpi by flow cytometry. (A) Expression of the CD69 activation marker on CD4⁺ and CD8⁺ T cells. (B) Expression of MHC class I (H-2K^s) and II (I-A^s) on CD11b⁺ cells (microglia and macrophages). Numbers in the FACS plots represent Mean Fluorescence Intensity. Expressions of CD40 (C) and PDL-1 (D) on CNS CD11b⁺ cells are shown. Numbers in the FACS plots represent percentages in total CD11b⁺ cells. (E) Expression of Foxp3 on CD4⁺ cells. Numbers in FACS plots represent percentages of total CD4⁺ cells. Data are representative of three experiments using three mice per group.