Figure 3From: Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice IRF7 deficient mice had more CNS-infiltrating cells. A-C) Example of FACS profiles of CNS from IRF7-KO mice with EAE. FACS profiles show CD45highCD11b+ macrophages (A), CD4+ T cells (B), and CD8+ T cells (C). IRF7-KO mice (n = 7) had more infiltrating CD45highCD11b+ macrophages (D), CD4+ (E) and CD8+ (F) cells in the CNS compared to WT mice (n = 6).Back to article page