Figure 1From: Insulin-like growth factor-I gene delivery to astrocytes reduces their inflammatory response to lipopolysaccharide Schematic representation of the construction of the RAd-IGF-I and RAd-TK/GFP adenoviral vectors. PmCMV, mouse cytomegalovirus promoter; IGF-I, cDNA for rat IGF-1; TK/GFP, hybrid DNA sequence encoding the fusion protein TK/GFP; ITR, inverted terminal repeat; ΔE1 and ΔE3, deletions in the AD5 genome; SV40, simian virus 40 polyadenylation signal; Ψ, packaging signal.Back to article page