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Table 2 CSF-albumin/S-albumin ratios and chemokine intrathecal production indices for the different patient groups¤.

From: Indications of Th1 and Th17 responses in cerebrospinal fluid from patients with Lyme neuroborreliosis: a large retrospective study

  Group 1
Confirmed NB
n = 133
Group 2
Possible late NB
n = 19
Group 3
Possible early NB
n = 15
Group 4
Non-NB
n = 96
CXCL8 index
median, (range)
0.23*
(0.01-2.3)
0.11
(0.01-0.5)
4.56***
(0.19-8.63)
0.16
(0-7.40)
CXCL10 index
median, (range)
3.13***
(0-76.7)
0.42
(0.02-1.08)
14.4***
(5.21-96.4)
0.59
(0-10.9)
CCL22 index
median, (range)
0.30***
(0-7.00)
0.07
(0-0.20)
0.20***
(0-2.00)
0.10
(0-7.00)
  1. Chemokine index: (CSF-chemokine/S-chemokine)/(CSF-albumin/S-albumin).
  2. NB: neuroborreliosis.
  3. n: number of patients.
  4. CSF: cerebrospinal fluid.
  5. S: serum.
  6. ¤: Indices could not be calculated for group 5, since CSF-albumin/S-albumin ratios were not available for all.
  7. The CCL22 index was multiplied by 100 due to much higher concentrations in serum.
  8. The IL-17 index was not calculated since IL-17 was not detectable in CSF in groups 2, 3 and 4.
  9. * significant differences compared to the non-NB group (group 4). * p < 0.01, ** p < 0.001, *** p < 0.0001.