Vascular endothelial growth factor-A (VEGF-A) and chemokine ligand-2 (CCL2) in amyotrophic lateral sclerosis (ALS) patients

Table 2 Crude and adjusted OR for VEGF-A levels in smokers, alcohol and meat consumers

	OR (95% CI)^†	p*	Adj. OR (95% CI) ^‡	p*
Serum VEGF-A
Smoking	1.4 (0.4-4.5)	0.5	0.7 (0.2-2.5)	0.6
Alcohol consumption	0.7 (0.2-2.2)	0.6	0.9 (0.3-3.0)	0.9
Meat consumption	1.5 (0.5-3.9)	0.4	1.4 (0.5-4.0)	0.7
CSF VEGF-A
Smoking	1.4 (0.4-4.5)	0.4	0.7 (0.2-2.5)	0.6
Alcohol consumption	0.7 (0.2-2.2)	0.4	0.9 (0.3-3.0)	0.8
Meat consumption	1.5 (0.5-3.9)	0.2	1.4 (0.5-4.0)	0.2
Never smoking/Nonalcoholic/Vegetarian**	1.0		1.0

† Univariate logistic regression was used to evaluate crude OR. ‡ Multivariate logistic regression has been used to adjust the effect of smoking on VEGF-A levels with alcohol and meat consumption as covariates. Likewise, effect of alcohol is adjusted for smoking and meat consumption, and meat consumption is corrected for smoking and alcohol intake. * χ² (chi square test) was used to test the level of significance. ** Never smoking, nonalcoholic and vegetarian diet is considered as reference group. OR, odds ratio; CI, confidence interval; Adj, adjusted.

ISSN: 1742-2094