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Figure 9 | Journal of Neuroinflammation

Figure 9

From: Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis

Figure 9

The spinal cord of Axl-/- mice has more axonal damage in the ventral and dorsal funiculi than WT mice. Seven micron paraffin-embedded WT and Axl-/- spinal cord sections were stained with SMI32, a mAb for non-phosphorylated neurofilaments. Representative 20× images are shown for the ventral and dorsal funiculi of WT and Axl-/- mice. b) SMI32+ non-phosphorylated neurofilament deposits were counted in the ventral and dorsal funiculi of three WT and three Axl-/- mice. Three or four sections were counted for each mouse and averaged. A student's t-test was performed to test significance; * = p < 0.05, # = p < 0.01.

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Journal of Neuroinflammation

ISSN: 1742-2094