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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures

Figure 2

Immunoreactivity of P T451 -PKR in mixed co-cultures. Representative blots showed immunoreactivity of PT451-PKR and actin in nuclear extracts of astrocyte/neuron/microlgia co-cultures treated with either 210 nM C16 or DMSO and exposed to 20 μM Aβ42 for 72 hours at 37°C. Wells of blots correspond to DMSO, C16, Aβ42 and DMSO, Aβ42 and C16, from left to right. Data are reported relative to actin. Results are expressed as percentage of DMSO control (set at 100%) and are mean ± SEM for 4 experiments. #p < 0.05, ***p < 0.001 compared to respective controls without C16 by one-way ANOVA with a Newman-Keuls multiple comparison test.

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Journal of Neuroinflammation

ISSN: 1742-2094