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Table 1 List of molecules in T cell-related canonical pathways in CCI

From: Immunodominant fragments of myelin basic protein initiate T cell-dependent pain

Biological function

Pvalue

Molecules

Infectious disease

2.41E-03 to 4.67E-02

AFG3L2, AHCTF1, ALKBH3, BCLAF1, C1R, DDX23, DPM1, ETHE1, FLII, GANAB, HLA-DQB1, IMPDH1, MAPT, MERTK, NUP62, PPP3CA, PPP3CB, PYCRL, RAB6A, RANBP2, RPL10A (includes EG:4736), SFRS2, STXBP1, STXBP1, TIMM8A, TOP2B, TPPP, TPPP, USP39, ZMPSTE24

CD28 signaling in T-helper cells

1.25E-02

FYN, HLA-DQB1, PDPK1, PPP3CA, PPP3CB, PTPN6

Calcium-induced T lymphocyte apoptosis

3.87E-03

ATP2A3, HLA-DQB1, PPP3CA, PPP3CB, PRKCI

  1. Ingenuity pathway analysis of the 2D-LC-MS/MS sciatic nerve proteome (day 7) after sham operation (normal) or CCI. P values for each biological function calculated by Fisher’s exact test are indicated.
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Journal of Neuroinflammation

ISSN: 1742-2094