Figure 8

Differential expression of NK1.1 in abscess-associated tissue. Abscess-associated cells from IL-17 receptor (IL-17R) knockout (KO) and wild-type (WT) mice (n = 5 to 9 per group) were recovered at days 7 (a) and 14 (b) after infection and analyzed by flow cytometry to identify NK1.1^high and NK1.1^low infiltrates. Representative contour plots depict differences in population densities between IL-17R WT and KO mice. Post-analysis gates were drawn around NK1.1^high (red) and NK1.1^low (green) populations in the top panel (NK1.1 versus NKp46) and corresponding populations can be seen in the bottom panel (NK1.1 versus γδ TCR). These populations were quantified at days 7 (c) and 14 (d) after infection and are expressed as the absolute number of each population recovered from four independent experiments (mean ± SD). **P < 0.01, significant differences between IL-17R KO and WT mice.