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Table 5 Time to relapse if disease started either with ON or MY.

From: Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

 

Time (median, range, N)

p-level

1st → 2nd attack†

  

   All patients

8.5 months (1-216; N = 138)

n.a.

Patients meeting Wingerchuk's 2006

criteria

9 months (1-216; N = 97)

n.a.

   Seropositives

9 months (1-201; N = 113)

n.s.

   Seronegatives

5 months (1-216; N = 25)

 

   ON at onset

17 months (1-208; N = 67)

p < 0.002§

   MY at onset

6 months (1-216; N = 61)

 

   MY+ON at onset

3.5 months (1-8; N = 10)

 

   Brainstem encephalitis at onset

5 months (2-20; N = 4)

 

1st ON → 2nd ON

24 months (1-381; 79)

p < 0.0001§

1st MY → 2nd MY

7 months (0-296; 121)

 

1st ON → 1st MY

14 months (0-349; 85)

p < 0.0005§

1st MY → 1st ON

3 months (0-217; 41)

 
  1. †Irrespective of whether the first event was ON or MY or simultaneous ON and MY. §Mann Whitney U test. N = number of patients (not all data were available from all patients); n.a. = not applicable; n.s. = not significant.