| Seropositive | Seronegative | p-level |
---|---|---|---|
Annualized ON relapse rate†|  |  |  |
   All patients with a history of ON | 0.38 (0.04-2.25; N = 83) | 0.36 (0.08-3; N = 21) | n.s.§ |
Patients meeting Wingerchuk's 2006 criteria | 0.37 (0.04-2.25; N = 80) | 0.25 (0.08-3; N = 19) | n.s.§ |
Bilateral ON ever | Â | Â | Â |
   All patients with a history of ON | 25/92 (27.2%) | 15/29 (51.7%) | p < 0.023‡ |
Patients meeting Wingerchuk's 2006 criteria | 23/87 (26.4%) | 14/27 (51.9%) | p < 0.019‡ |
Bilateral ON at first ON attack* | Â | Â | Â |
   All patients with a history of ON | 12/85 (14.1%) | 11/28 (39.3%) | p < 0.007‡ |
Patients meeting Wingerchuk's 2006 criteria | 12/81 (14.8%) | 10/26 (38.5%) | p < 0.023‡ |
ON attacks with VA ≤ 0.1 |  |  |  |
   All patients with a history of ON | 83/123 (67.5%) | 13/35 (37.1%) | p < 0.002‡ |
Patients meeting Wingerchuk's 2006 Criteria | 74/112 (66.1%) | 12/33 (36.4%) | p < 0.005‡ |
Attacks with complete recovery | Â | Â | Â |
   All patients with a history of ON | 68/205 (33.2%) | 15/51 (29.4%) | n.s.‡ |
Patients meeting Wingerchuk's 2006 Criteria | 64/190 (33.7%) | 13/42 (31%) | n.s.‡ |