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Table 1 Changes (percent composition) in rat brain sphingomyelin molecular species following intraventricular infusion with propionic acid (PPA) and phosphate buffered saline (PBS)

From: The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders

Molecular weight Molecular species Base/acyl species PBS PPA
703 34:1 18:1/16:0 0.07 ± 0.03 0.10 ± 0.05
733 36:0 18:0/18:0 21.96 ± 0.35 39.13 ± 1.35*
731 36:1 18:1/18:0 6.21 ± 0.67 4.53 ± 1.28
761 38:0 18:0/20:0 38.09 ± 0.84 29.37 ±1.92*
759 38:1 18:1/20:0 16.08 ± 0.19 12.31 ± 3.64*
789 40:0 18:0/22:0 13.03 ± 0.24 9.92 ± 1.31*
811 42:3 18:1/24:2 4.56 ± 0.12 4.64 ± 1.54
Total%    100 100
∑ Saturates    73.07 ± 0.15 78.41 ± 1.44*
∑ Monounsat    22.37 ± 0.66 16.94 ± 2.91*
∑ Polyunsat    4.55 ± 0.12 4.63 ± 1.54
  1. Values (nanomole percent by weight composition) represent means ± standard errors. Means in the same row accompanied by asterisks are significantly different between treatments at LSD = 0.05, n = 12 per treatment group. Monounsat, monounsaturated fatty acids; PBS, phosphate buffered saline solution; PPA, propionic acid; polyunsat, polyunsaturated fatty acids. Sphingomyelin molecular species were identified using a precursor ion scan of m/z 184 in ESI positive mode. The lipid components in the table are arranged based on the molecular species composition.