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Table 10 Changes (nanomole percent by weight composition) in rat plasma phosphatidylethanolamine molecular species following intraventricular infusion with propionic acid (PPA) and phosphate buffered saline (PBS)

From: The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders

Molecular weight Molecular species Plasmalogen or diacyl species PBS PPA
702 P34:1 p16:0/18:1 4.59 ± 0.43 3.51 ± 0.53
716 D34:2 16:0/18:2 4.42 ± 0.13 4.41 ± 0.66
732 P36:0 p18:0/18:0 4.39 ± 0.19 3.11 ± 0.41*
746 D36:1 18:0/18:1 4.55 ± 0.44 3.38 ± 0.49*
730 P36:1 p18:0/18:1 5.76 ± 0.56 3.57 ± 0.50 *
744 D36:2 18:0/18:2 5.20 ± 0.58 4.49 ± 0.55
728 P36:2 p18:0/18:2 3.10 ± 1.36 3.19 ± 0.26
726 P36:3 p18:1/18:2 4.28 ± 0.19 3.85 ± 0.36
724 P36:4 p16:0/20:4 4.47 ± 0.42 3.41 ± 0.46*
768 D38:4 18:0/20:4 10.82 ± 0.71 23.60 ± 4.93*
752 P38:4 p18:0/20:4 4.67 ± 0.06 3.70 ± 0.45*
764 D38:6 16:0/22:6 5.35 ± 0.21 7.02 ± 0.56*
748 P38:6 p16:0/22:6 4.87 ± 0.38 3.71 ± 0.64
798 D40:3 18:0/22:3 4.27 ± 0.34 3.92 ± 0.68
796 D40:4 20:0/20:4 4.78 ± 0.29 3.67 ± 0.62
780 P40:4 p18:0/22:4 4.06 ± 0.17 3.41 ± 0.34
794 D40:5 18:0/22:5 4.97 ± 0.35 4.07 ± 0.32
778 P40:5 p18:0/22:5 4.67 ± 0.27 3.76 ± 0.83
792 D40:6 18:0/22:6 5.89 ± 0.62 7.03 ± 1.63
776 P40:6 p18:0/22:6 4.80 ± 0.33 3.54 ± 0.69*
Total%    100 100
∑ Saturates    4.39 ± 0.19 3.11 ± 0.41*
∑ Monounsat    14.92 ± 0.39 10.46 ± 1.46*
∑ Polyunsat    80.68 ± 0.43 86.41 ± 1.81*
∑ Plas    49.69 ± 0.96 38.37 ± 3.81*
  1. Values (nanomole percent by weight composition) represent means ± standard errors. Means in the same row accompanied by asterisks are significantly different between treatments at LSD = 0.05, n = 12 per treatment group. D represents diacyl species and P represents plasmalogens species, p denotes a sn-1 vinyl ether (plasmalogen) linkage. Monounsat, monounsaturated fatty acids; PBS, phosphate buffered saline solution, plas, plasmalogens; polyunsat, polyunsaturated fatty acids; PPA, propionic acid. Phosphatidylethanolamine molecular species were identified using neutral loss scan of 141 D in ESI positive mode. The lipid components in the table are arranged based on the molecular species composition.