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Table 3 Changes (percent composition) in rat brain phosphatidylcholine molecular species following intraventricular infusion with propionic acid (PPA) and phosphate buffered saline (PBS)

From: The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders

Molecular weight Molecular species Plasmalogen or diacyl species PBS PPA
706 D30:0 16:0/14:0 0.13 ± 0.055 0.13 ± 0.04
734 D32:0 16:0/16:0 19.23 ± 0.34 19.33 ± 0.69
718 P32:1 p16:0/16:1 0.05 ± 0.01 0.06 ± 0.01
762 D34:0 16:0/18:0 18.66 ± 0.49 19.14 ± 0.63
760 D34:1 16:0/18:1 32.80 ± 0.15 33.68 ± 0.16*
746 P34:1 p16:0/18:1 1.54 ± 0.26 1.40 ± 0.32
758 D34:2 16:0/18:2 0.27 ± 0.04 0.69 ± 0.19*
788 D36:1 18:0/18:1 10.53 ± 0.18 9.20 ± 0.15*
774 P36:1 p18:0/18:1 0.50 ± 0.11 0.40 ± 0.11
782 D36:4 16:0/20:4 3.96 ± 0.51 4.81 ± 0.53*
814 D38:2 18:1/20:1 1.21 ± 0.25 1.29 ± 0.11
812 D38:3 18:0/20:3 1.85 ± 0.28 1.74 ± 0.14
810 D38:4 18:0/20:4 4.91 ± 0.26 4.33 ± 0.34
806 D38:6 16:0/22:6 2.98 ± 0.12 2.74 ± 0.10
834 D40:6 18:0/22:6 1.36 ± 0.11 1.06 ± 0.14
Total%    100 100
∑ Saturates    18.78 ± 0.48 19.27 ± 0.60
∑ Monounsat    62.56 ± 0.51 62.20 ± 0.70
∑ Polyunsat    16.55 ± 0.63 16.65 ± 0.99
∑ Plas    2.09 ± 0.32 1.85 ± 0.43
  1. Values (nanomole percent by weight composition) represent means ± standard errors. Means in the same row accompanied by asterisks are significantly different between treatments at LSD = 0.05, n = 12 per treatment group. D represents diacyl species and P represents plasmalogens species, p denotes a sn-1 vinyl ether (plasmalogen) linkage. Monounsat, monounsaturated fatty acids; PBS, phosphate buffered saline solution; plas, plasmalogens; polyunsat, polyunsaturated fatty acids; PPA, propionic acid. Phosphatidylcholine molecular species were identified using a precursor ion scan of m/z 184 in ESI positive mode.