Skip to main content

Table 7 Changes (nanomole percent by weight composition) in rat brain phosphatidylserine molecular species following intraventricular infusion with propionic acid (PPA) and phosphate buffered saline (PBS)

From: The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders

Molecular weight Molecular species Diacyl species PBS PPA
760 D34:1 16:0/18:1 0.90 ± 0.10 1.10 ± 0.21
790 D36:0 18:0/18:0 1.59 ± 0.41 1.65 ± 0.11
788 D36:1 18:0/18:1 18.10 ± 0.53 21.62 ± 0.63*
786 D36:2 18:0/18:2 2.36 ± 0.34 2.55 ± 0.17
816 D38:1 18:0/20:1 1.00 ± 0.15 1.22 ± 0.19
810 D38:4 18:0/20:4 4.18 ± 0.07 4.46 ± 0.12
840 D40:3 18:0/22:3 1.19 ± 0.23 1.20 ± 0.17
838 D40:4 18:0/22:4 4.67 ± 0.17 3.63 ± 0.14*
836 D40:5 18:0/22:5 6.40 ± 0.30 6.91 ± 0.43
834 D40:6 18:0/22:6 58.39 ± 0.98 54.49 ± 1.05*
832 D40:7 18:1/22:6 1.22 ± 0.08 1.17 ± 0.12
Total%    100 100
∑ Saturates    1.59 ± 0.15 1.65 ± 0.11
∑ Monounsat    19.99 ± 0.39 23.93 ± 0.66*
∑ Polyunsat    78.41 ± 0.58 74.45 ± 0.55*
  1. Values (nanomole percent by weight composition) represent means ± standard errors. Means in the same row accompanied by asterisks are significantly different between treatments at LSD = 0.05, n = 12 per treatment group. D represents diacyl species. Monounsat, monounsaturated fatty acids; PBS, phosphate buffered saline solution; polyunsat, polyunsaturated fatty acids; PPA, propionic acid. Phosphatidylserine molecular species were identified using neutral loss scan of 87 D in ESI negative mode. The lipid components in the table are arranged based on the molecular species composition.