Figure 2

Correlation of preactive lesions with the occurrence of white matter lesions. Presence of preactive lesions (PAL) in tissue blocks in NAWM (A) or blocks containing active and chronic active lesions (B). The numbers of blocks of NAWM (A) or active lesions (B) were expressed as percentage of all blocks. Pearson correlation testing was performed for respective groups. The presence of preactive lesions negatively correlates with the number of blocks containing no lesions (p = 0.0128; R² 0.28), whereas the presence of preactive lesions positively correlates with the number of active lesions (p = 0.049; R² 0.19). Frequency of preactive lesions were determined in respective lesions and results compared using one-way ANOVA followed by Tukey’s multiple comparison test. A tendency exists that preactive lesions are more frequently observed in blocks containing active and chronic active lesions compared to blocks containing no lesion or chronic inactive lesions; however, this failed being statistically significant (C).