Figure 12
From: Activation of TRPV1 by capsaicin induces functional Kinin B1 receptor in rat spinal cord microglia
Control and capsaicin (CAPS, 15 mg/kg, s.c.)-injected rats were pre-treated for 7 days with N-acetyl-L-cysteine (NAC, 1 g/kg/d) or its vehicle. Protein expression for B1R (37 kDa), p65NF-κB (65 kDa) and dynein (70 kDa) was measured on lumbar spinal cord by western blot. Representative immunoblots are shown in the upper panels while densitometric quantifications of protein expression are shown in lower panels. Data represent the means ± S.E.M. of 3-4 rats in each group. Comparison with control + vehicle (*) or capsaicin + vehicle (+) is indicated by ** ++ P < 0.01.