Figure 19
From: Time-dependent effects of hypothermia on microglial activation and migration
Inhibition of proinflammatory cytokine and iNOS expression by local hypothermia in the rat model of stab injury. After the focal stab injury in the cortex under normothermia or hypothermia as described in the main text (A), cortical tissues were prepared and subjected to RT-PCR analysis (B). Compared to normothermia, hypothermia diminished the injury-induced expression of TNF-α, IL-1β, and iNOS. iNOS, inducible NO synthase.