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Figure 7 | Journal of Neuroinflammation

Figure 7

From: Regulatory effects of the JAK3/STAT1 pathway on the release of secreted phospholipase A2-IIA in microvascular endothelial cells of the injured brain

Figure 7

Effects of WHI, Flu, and siRNA STAT1 on the release of sPLA 2 -IIA from BMVECs and enzymatic activity of sPLA 2 . (A) Effects of WHI, Flu, and siRNA STAT1 on the release of sPLA2-IIA from the cells after LPS treatment for 16 h. Representative bands (upper panel) are shown of the Western blotting results for sPLA2-IIA and BSA protein in the medium after LPS treatment with WHI and Flu or STAT1 siRNA. (B) Quantitative data of sPLA2 enzyme activity after LPS and treatment with WHI, Flu, and siRNA STAT1 are shown in the histogram. The data are presented as the means ± SE of five separate experiments. *P < 0.05 versus the normal group, ^ P < 0.05 versus LPS treatment alone group.

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