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Table 1 CD73−/− mice develop less severe EAE compared to WT mice A

From: Extracellular adenosine signaling induces CX3CL1 expression in the brain to promote experimental autoimmune encephalomyelitis

  IncidenceB Mean Day of OnsetC Mean Max EAE ScoreD
WT 8/8 10.8 (8 – 14) 2.9 (1.5 – 5.0)
CD73−/− 6/10 12.7 (9 – 17) 1.1 (0.0 – 2.0) *
  1. A. Wild type and CD73−/− mice were induced to develop EAE and scored daily for EAE severity based on the 5 point scale assessing ascending paralysis.
  2. B. Indicates the number of mice that achieved a score of 0.5 (weak tail) in the experimental group.
  3. C. Indicates the average day of onset for the mice that developed EAE (a score of 0.5) followed by the range of scores in parentheses. Mice that did not develop disease were excluded.
  4. D. Indicated the average of the maximum EAE score for each individual mouse followed by the range of scores in parentheses (* = p < 0.01; Student’s T-test).