Figure 5

Constitutive exposure of CRT at the neuronal surface is not modulated during priming of neurons. (A) Surface biotinylation of primed neurons (see Figure 1A) reveals that CRT is externalised to equal extent on both primed and unprimed neurons. (B) Peroxynitrite, which induces PS flip on viable neurons, does not alter surface expression of CRT on neurons. CRT, calreticulin; PS, phosphatidylserine.