Figure 2
From: Neuroexcitatory effects of morphine-3-glucuronide are dependent on Toll-like receptor 4 signaling
Calcium imaging of functional Toll-like receptor 4 signaling in cultured dorsal root ganglion neurons. (A) Toll-like receptor 4 (TLR4)-IR (green) is largely restricted to neurons and not non-neuronal cell types (blue, DAPI) in dissociated dorsal root ganglion (DRG) cultures. (B) Representative recording of a transient intracellular calcium increase in a dissociated DRG sensory neuron via lipopolysaccharide (LPS) administration (1 μg/mL).