Figure 3

Hippocampal expression patterns of IL-25 and CCL4 in Control, mTLE-HS and mTLE + HS patients. Photomicrographs showing typical examples of Il-25 and CCL4 staining in the hippocampal CA1 region (A) and the DG/CA4 region (B). IL-25 immunoreactivity (IR) is evident in cells with neuronal morphology in all three patient groups (A, B); note the increased IL-25 staining in the mTLE + HS hippocampus in small cells. CCL4 IR is low in controls (A, B). Increased CCL4 IR is detected in both mTLE patient groups in the DG-CA4 area (B) and in the CA1 area of mTLE + HS patients (A). Scale bar = 200 μm.The insets are higher power magnifications taken from the same anatomical area