Figure 7 From: Neuroinflammation and oxidative stress in rostral ventrolateral medulla contribute to neurogenic hypertension induced by systemic inflammation Oxidative stress in RVLM underpins hypertension induced by intraperitoneal infusion of LPS. Changes in MSAP (A,B) or plasma level of CRP (C) determined on day 7 after intraperitoneal infusion of saline or LPS (1.2 mg/kg/day), alone or with additional intracisternal infusion of aCSF or tempol (1μmol/μL/h) (A,C), or microinjection bilaterally into RVLM of tempol (100 pmol) (B). Values are mean ± SEM (n=8 to 10 animals in each experimental group). *P <0.05 vs. saline-treatment or sham-control group; # P <0.05 vs. LPS-treatment group in the post hoc Scheffé multiple-range test.Back to article page