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Table 1 Microglial release of cytokines

From: Selective targeting of microglia by quantum dots

  TNFα IL-1α IL-1β IL-6 KC RANTES G-CSF MCP-1 MIP-1α MIP-1β IP-10
Ctrl 0.9 ± 0.5 ND ND 2.3 ± 1.7 1.4 ± 0.8 2.3 ± 1.7 ND ND 2.4 ± .9 3.8 ± 1.5 54.6 ± 35.3
(n = 3)            
Qdots 0.3 ± 0.1 ND ND ND 0.5 ± 0.1 1.2 ± 0.01 ND ND 1.5 ± 1.0 3.2 ± 3.0 17.6 ± 9.8
(n = 2)            
LPS 226.5 ± 9.4 6.3 ± 3.2 1.7 ± 0.8 471.9 ± 34.6 345.5 ± 21.0 391.8 ± 19.0 53.9 ± 9.3 12.1 ± 7.2 592.7 ± 76.3 500.0 ± 23 189.8 ± 14.2
(n = 3)            
LPS+ 217.1 ± 47.4 9.6 ± 6.9 2.6 ± 2.1 533 ± 197.5 363.5 ± 89.4 394.5 ± 84.2 49.4 ± 5.3 20.7 ± 17.9 637.3 ± 263.5 519.2 ± 169.0 196.0 ± 53.9
Qdots (n = 2)            
  1. Cytokines (pg/ml) released by primary microglia treated with vehicle, QD, LPS, or LPS + QD (mean ± SEM). n, number of wells per condition. ND not detected, G-CSF granulocyte colony-stimulating factor, IP-10 10 kDa interferon-gamma-induced protein, KC, keratinocyte chemoattractant, MCP-1 monocyte chemotactic protein-1, MIP-1α macrophage inflammatory protein 1 alpha, MIP-1β macrophage inflammatory protein 1 beta, RANTES, regulated upon activation. The following cytokines were undetectable in all conditions: VEGF, IFNγ, and IL-10