Figure 4

Novel place and novel object recognition test. (A). Novel place recognition familiarization phase. Analysis of the total amount of object exploration showed no significant difference across experimental groups. (B). 5 min delay novel place recognition. aCSF-vehicle, aCSF-DT and LPS-DT rats showed a preference for the novel place recognition over the familiar location (*p < 0.05 and **p < 0.01 vs. familiar place) whereas LPS-vehicle rats did not. (C). 24 h delay novel place recognition. aCSF-vehicle and aCSF-DT showed a preference for the novel place recognition over the familiar location (*p < 0.05 and ***p < 0.001 vs. familiar place) whereas LPS-vehicle and LPS-DT rats did not (D). Novel object recognition. aCSF-vehicle, aCSF-DT, LPS-vehicle and LPS-DT rats all showed a preference for the novel object over the familiar one (*p < 0.05; **p < 0.01; ***p < 0.001 vs. familiar object).