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Table 1 Standard uptake value of 11 C-[R]-PK11195 in various brain regions

From: Evaluation of age-related changes in translocator protein (TSPO) in human brain using 11C-[R]-PK11195 PET

  

SUV5 to 20 minutes (mean ± SD (95%CI))

 

Side

Adults (n = 15)

Children (n = 10)

P

Pituitary gland

 

1.04 ±0.19 (1.27 to 1.53)

1.01 ±0.43 (0.60 to 2.09)a

0.97

Midbrain

 

1.11 ±0.17 (1.01 to 1.2)

0.9 ±0.21 (0.75 to 1.01)

0.001

Thalamus

Left

1.09 ±0.14 (1.01 to 1.17)

0.84 ±0.23 (0.67 to 1)

0.002

Right

1.08 ±0.12 (1.02 to 1.15)

0.84 ±0.24 (0.67 to 1.01)

0.002

Lentiform nucleus

Left

1.0 ±0.12 (0.94 to 1.07)

0.78 ±0.19 (0.65 to 0.92)

0.002

 

Right

0.97 ±0.15 (0.89 to 1.05)

0.76 ±0.2 (0.62 to 0.91)

0.006

Caudate

Left

0.93 ±0.11 (0.87 to 0.99)

0.73 ±0.17 (0.61 to 0.85)

0.001

 

Right

0.92 ±0.11 (0.86 to 0.99)

0.73 ±0.17 (0.60 to 0.85)

0.002

Hippocampus

Left

0.88 ±0.11 (0.82 to 0.94)

0.69 ±0.17 (0.57 to 0.81)

0.002

 

Right

0.87 ±0.11 (0.81 to 0.93)

0.69 ±0.16 (0.57 to 0.81)

0.002

Cerebellum

Left

0.97 ±0.11 (0.91 to 1.03)

0.77 ±0.2 (0.63 to 0.91)

0.003

 

Right

0.99 ±0.12 (0.92 to 1.05)

0.76 ±0.20 (0.62 to 0.90)

0.001

Frontal cortex

Left

0.95 ±0.11 (0.88 to 1.01)

0.73 ±0.17 (0.61 to 0.86)

0.001

 

Right

0.94 ±0.11 (0.88 to 1.00)

0.73 ±0.17 (0.61 to 0.85)

0.001

Parietal cortex

Left

0.87 ±0.11 (0.81 to 0.93)

0.68 ±0.17 (0.56 to 0.8)

0.002

 

Right

0.87 ±0.11 (0.81 to 0.93)

0.68 ±0.17 (0.56 to 0.8)

0.002

Temporal cortex

Left

0.86 ±0.10 (0.80 to 0.92)

0.68 ±0.17 (0.55 to 0.8)

0.002

 

Right

0.85 ±0.11 (0.79 to 0.91)

0.68 ±0.16 (0.56 to 0.8)

0.005

Occipital cortex

Left

0.91 ±0.11 (0.85 to 0.98)

0.68 ±0.19 (0.54 to 0.82)

0.001

 

Right

0.88 ±0.09 (0.82 to 0.93)

0.69 ±0.19 (0.55 to 0.82)

0.003

  1. aPituitary SUV values available in three children only, as it could not be estimated in seven children because of an inability to reliably delineate the pituitary from the surrounding lymphoid tissue/circular venous plexus in these children. CI confidence intervals; SD standard deviation; SUV standard uptake value.