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Table 1 Standard uptake value of 11 C-[R]-PK11195 in various brain regions

From: Evaluation of age-related changes in translocator protein (TSPO) in human brain using 11C-[R]-PK11195 PET

   SUV5 to 20 minutes (mean ± SD (95%CI))
  Side Adults (n = 15) Children (n = 10) P
Pituitary gland   1.04 ±0.19 (1.27 to 1.53) 1.01 ±0.43 (0.60 to 2.09)a 0.97
Midbrain   1.11 ±0.17 (1.01 to 1.2) 0.9 ±0.21 (0.75 to 1.01) 0.001
Thalamus Left 1.09 ±0.14 (1.01 to 1.17) 0.84 ±0.23 (0.67 to 1) 0.002
Right 1.08 ±0.12 (1.02 to 1.15) 0.84 ±0.24 (0.67 to 1.01) 0.002
Lentiform nucleus Left 1.0 ±0.12 (0.94 to 1.07) 0.78 ±0.19 (0.65 to 0.92) 0.002
  Right 0.97 ±0.15 (0.89 to 1.05) 0.76 ±0.2 (0.62 to 0.91) 0.006
Caudate Left 0.93 ±0.11 (0.87 to 0.99) 0.73 ±0.17 (0.61 to 0.85) 0.001
  Right 0.92 ±0.11 (0.86 to 0.99) 0.73 ±0.17 (0.60 to 0.85) 0.002
Hippocampus Left 0.88 ±0.11 (0.82 to 0.94) 0.69 ±0.17 (0.57 to 0.81) 0.002
  Right 0.87 ±0.11 (0.81 to 0.93) 0.69 ±0.16 (0.57 to 0.81) 0.002
Cerebellum Left 0.97 ±0.11 (0.91 to 1.03) 0.77 ±0.2 (0.63 to 0.91) 0.003
  Right 0.99 ±0.12 (0.92 to 1.05) 0.76 ±0.20 (0.62 to 0.90) 0.001
Frontal cortex Left 0.95 ±0.11 (0.88 to 1.01) 0.73 ±0.17 (0.61 to 0.86) 0.001
  Right 0.94 ±0.11 (0.88 to 1.00) 0.73 ±0.17 (0.61 to 0.85) 0.001
Parietal cortex Left 0.87 ±0.11 (0.81 to 0.93) 0.68 ±0.17 (0.56 to 0.8) 0.002
  Right 0.87 ±0.11 (0.81 to 0.93) 0.68 ±0.17 (0.56 to 0.8) 0.002
Temporal cortex Left 0.86 ±0.10 (0.80 to 0.92) 0.68 ±0.17 (0.55 to 0.8) 0.002
  Right 0.85 ±0.11 (0.79 to 0.91) 0.68 ±0.16 (0.56 to 0.8) 0.005
Occipital cortex Left 0.91 ±0.11 (0.85 to 0.98) 0.68 ±0.19 (0.54 to 0.82) 0.001
  Right 0.88 ±0.09 (0.82 to 0.93) 0.69 ±0.19 (0.55 to 0.82) 0.003
  1. aPituitary SUV values available in three children only, as it could not be estimated in seven children because of an inability to reliably delineate the pituitary from the surrounding lymphoid tissue/circular venous plexus in these children. CI confidence intervals; SD standard deviation; SUV standard uptake value.
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