Figure 4

The effect of acetate supplementation on B. burgdorferi -induced increases in brain IL-1β. Panel (A) represents the time-dependent changes in serum IL-1β between the day of inoculation (day 0) and 28 days post-infection showing infected rats treated with either water or glyceryl triacetate (GTA). Panel (B) represents serum IL-1β levels at 28 days post-infection in naïve and infected rats treated with either water or GTA. Panel (C) shows a representative image of the IL-1β and α tubulin western blots and panel (D) represents the composite analysis of the western blot analysis brain IL-1β in naïve and infected rats treated with either water or GTA. Values represent the means ± SD with a sample size of seven, six and five per group, respectively. The asterisk (*) represents a significant difference comparing GTA-treated rats to water-treated rats.