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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Exacerbation of experimental autoimmune encephalomyelitis in prion protein (PrPc)-null mice: evidence for a critical role of the central nervous system

Figure 1

Exacerbated EAE in PrPc-ablated ( Prnp -/- ) mice. Clinical scores (mean ± SEM) in PrPc-deficient (black dots) versus PrP-sufficient (black triangles) mice. Disease onset was identical in the two groups (Prnp -/-: 12.7 ± 0.3; Prnp +/+: 12.4 ± 0.4). Clinical scores began significantly diverging at 22 dpi after the initial peak of disease. *: p < 0.05 by Mann-Whitney (n = 8-10/group).

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Journal of Neuroinflammation

ISSN: 1742-2094