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Table 2 Kir4.1 and IL-1β immunoreactivity in astrocytic tumors

From: Regulation of Kir4.1 expression in astrocytes and astrocytic tumors: a role for interleukin-1 β

IR score

A II(n = 6)

A III(n = 12)

GBM (n = 55 )

Control cortex/autopsy (n = 8)

Control cortex/surgical (n = 5)

Kir4.1

3.6 ± 0.85*

7.18 ± 0.41

5.5 ± 0.30

7.13 ± 0.36

7.03 ± 0.26

IL-1β

2.46 ± 0.67*

3.9 ± 0.9*

3.75 ± 0.45*

0

0.02 ± 0.02

HLA-DR

5.4 ± 0.77*

5.7 ± 0.80*

5.83 ± 0.35*

0.04 ± 0.02

0.03 ± 0.02

  1. A II, Astrocytoma WHO grade II; A III, Astrocytoma WHO grade III; GBM, Glioblastoma multiforme.
  2. Values represent the average immunoreactive score (IR) ± SEM. *P <0.05 (compared to control cortex, both autopsy and surgical samples). Kir4.1 IR score for AIII > Kir4.1 score for AII (P <0.05).
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Journal of Neuroinflammation

ISSN: 1742-2094