Immunological characterization and transcription profiling of peripheral blood (PB) monocytes in children with autism spectrum disorders (ASD) and specific polysaccharide antibody deficiency (SPAD): case study

Table 3 Summary of transcription profiling results in ASD/SPAD children

Numbers of genes¹	Vs. normal controls	Vs. ASD/non-SPAD controls	Overlapping in 2 control groups
Up-regulated	830	1258	316
Down-regulated	653	1235	356
Pathway analysis	Vs. normal controls	Vs. ASD/non-SPAD controls
TGFBR	Not significant	P < 0.01
EGFR	Not significant	P < 0.02
NOTCH	Not significant	P < 0.005

¹ The number of genes > 2 fold up- or down-regulated in the ASD/SPAD children as compared to normal controls and ASD/non-SPAD children.

ISSN: 1742-2094