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Table 1 Irradiation bone marrow chimeric mice (BMC)

From: IFN-gamma signaling in the central nervous system controls the course of experimental autoimmune encephalomyelitis independently of the localization and composition of inflammatory foci

Donor mice

Recipient mice

BMC mice

IFNγRKO-CD45.2

IFNγRKO-CD45.2

IFNγRKO-chimeras

C57BL/6-CD45.1

IFNγRKO-CD45.2

IFNγRCNSKO

C57BL/6-CD45.1

C57BL/6-CD45.2

WT-chimeras

IFNγRKO-CD45.2

C57BL/6-CD45.1

IFNγRperiKO

  1. Radiosensitive (peripheral immune) cells carry the genotype of donor mouse, while radioresistant cells (all parenchymal cells including the CNS) carry the genotype of the recipient mouse.
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Journal of Neuroinflammation

ISSN: 1742-2094