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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Decreased MHC I expression in IFN gamma mutant mice alters synaptic elimination in the spinal cord after peripheral injury

Figure 2

The graph shows β2-microglobulin mRNA upregulation following unilateral sciatic nerve axotomy determined by RT-PCR (P < 0.05). The unlesioned side was used as reference (100%). (B) β2-microglobulin mRNA level in the lumbar spinal cord of IFNγ−/− mice. The graph shows a smaller β2-microglobulin mRNA upregulation following unilateral sciatic nerve axotomy determined by RT-PCR (P < 0.05), as compared to the wild type strain. The unlesioned side was used as reference (100%). (C) β2-microglobulin mRNA upregulation in C57BL/6J and IFNγ−/− mice (ratio ipsi/contralateral). Observe that the mutant mice display a smaller upregulation of β2-microglobulin following lesion. * = P < 0.05.

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Journal of Neuroinflammation

ISSN: 1742-2094