Table 1 Demographic data and CSF parameters

Demographic data

Samples

20

30

20

8

30

Samples for Immuno-phenotyping

CSF/Blood

19/13

30/28

20/15

8/3

30/24

Age (years)

32 (18 to 77)

31 (17 to 51)

38 (18 to 69)

57 (37 to 78)

41 (18 to 73)

Sex female/male

10/10

15/15

11/9

6/2

11/19

Phase of disease (Number of patients)

Acute^a symptoms (20)

Acute^a relapse (27), remission (3)

Acute^a relapse (15), remission (5)

Acute^a (6), chronic^b (2)

Acute^a (22), remission (2), unknown (6)

CSF parametes

CSF cell count per μl

2 (1 to 5)

7 (1 to 29)

7 (0 to 81)

106 (9 to 280)

33 (2 to 512)

Q_Albumin

5 (3.0 to 9.6)

5 (3.1 to 10.1)

5 (3.3 to 7.5)

12 (6.0 to 25.9)

8 (3.7 to 55.5)

Intrathecal IgG production

0/20

17/30

13/18

7/8

10/29

Intrathecal IgA production

0/20

0/30

2/18

5/8

9/29

Intrathecal IgM production

0/20

4/30

5/18

6/8

6/29

OCBs (+/-)

0/20

(25/0)^c

(19/1)

(6/2)

(13/17)

Impairment blood-CSF barrier

2/18

8/30

3/20

6/8

21/30