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Figure 7 | Journal of Neuroinflammation

Figure 7

From: Expression of 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) and its roles in activated microglia in vivo and in vitro

Figure 7

CNPase knockdown on cell cycle progression in BV-2 cells. (A) Representative DNA histogram plots from an individual experiment showing control small interfering RNA (siRNA) and CNPase siRNA transfected groups with and without lipopolysaccharide (LPS) treatment. (B) Percentage of total cells in each phase of cell cycle. CNPase knockdown arrested the cells in the G1 phase with a corresponding decrease in the percentage of cells entering into the S + G2/M phase. *P < 0.05 compared with controls by unpaired t-test, from three independent experiments. CNPase, 2′,3′-cyclic nucleotide 3′-phosphodiesterase.

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Journal of Neuroinflammation

ISSN: 1742-2094