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Figure 8 | Journal of Neuroinflammation

Figure 8

From: Neuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation

Figure 8

Effects of bilobalide on the levels of nitric oxide, TNF-Α, and IL-1Β in primary cortical neurons after OGD/R. (A) Pretreatment with bilobalide (50, 100 μM) significantly reduced nitric oxide (B) and TNF-Α (C) and IL-1Β levels in OGD/R-induced cortical neurons compared with the OGD/R group. Mean values ± standard error of the mean ** P < 0.01 versus control; # P < 0.05, ## P < 0.01 versus OGD/R. BB, bilobalide; OGD/R, oxygen-glucose deprivation and reoxygenation.

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Journal of Neuroinflammation

ISSN: 1742-2094