Skip to main content
Figure 1 | Journal of Neuroinflammation

Figure 1

From: The p38alpha mitogen-activated protein kinase limits the CNS proinflammatory cytokine response to systemic lipopolysaccharide, potentially through an IL-10 dependent mechanism

Figure 1

Microglia and mixed glia cultures from p38α ΔLysM-Cre knockout (KO) are less responsive to lipopolysaccharide (LPS). Wild-type (WT) (white) or p38αΔLysM-Cre KO (black) primary microglia (A) and mixed glia (B) were stimulated with LPS for 30 min, cells washed, and then conditioned media was harvested at select time points for TNFΑ Meso Scale Discovery (MSD) assays. The data are representative of three independent experiments. (*P <0.05; ***P <0.0005).

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094