Figure 10

Extravasation of RITC (red) in the olfactory bulb of the C group (A-C), the SI + S group at 24 h (D-F), and the SI + AG group at 24 h (G-I). In the C group, the olfactory bulb tissue emits very weak RITC fluorescence (B,C), which is also detected in GFAP-labeled astrocytes (arrow) in B. In the SI + S group and at 3 h after RITC administration, RITC fluorescence (asterisks) appears to permeate the neuropil (D-F). In some areas, extravasated RITC superimposes with the blood vessels (arrowhead) (F,I). In the SI + AG group, RITC leakage is moderately reduced, as shown by the attenuated fluorescence (G-I). Scale bar =20.0 μm).