Figure 1
From: Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia
Experimental design and analysis strategy. (A) Microfluidic devices or bioreactors were seeded with neurons or astroglia for 6 days prior to IL-6 exposure. (B) Illustration of the sample preparation method for bioreactor perfusate samples (control × IL-6, astroglia × IL-6, and neurons × IL-6). Samples were prepared for exometabolomic analyses and analysis performed using an ultra-performance liquid chromatography-ion mobility-mass spectrometer.