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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Cytokine profiles by peripheral blood monocytes are associated with changes in behavioral symptoms following immune insults in a subset of ASD subjects: an inflammatory subtype?

Figure 4

IL-1 ß produced in response to lipopolysaccharide (LPS) (Panel A) and zymosan (Panel B) and IL-6 in response to zymosan (Panel C) by `flare’ and `non-flare’ autism spectrum disorder-inflammatory subtype (ASD-IS) cells. The values were expressed as IL-1 ß or IL-10 produced with stimuli minus the values of IL-1 ß or IL-10 produced spontaneously. IL-1 ß production was higher by `flare’ ASD-IS cells than in ASD-IS `non-flare’ cells (P <0.005 and P <0.01, respectively). IL-6 production was lower in `flare’ ASD-IS cells than `non-flare’ cells (P <0.01) by Wilcoxin rank sum test.

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