Cytokine profiles by peripheral blood monocytes are associated with changes in behavioral symptoms following immune insults in a subset of ASD subjects: an inflammatory subtype?

Table 2 Comorbid conditions of the study subjects

	Seizure disorder	Autoimmune conditions	Allergic rhinitis	Asthma		Ab deficiency
ASD ^c subjects				Atopic	Non-atopic
ASD-IS (N = 24)	4/24	2/24^a	2/24	0	3/24	3/24^b
ASD/NFA (N = 20)	2/20	0	3/20	1/20	0	0
ASD/non-NFA (N = 20)	1/20	0	0	0	0	0
Non-ASD subjects
Non-ASD/NFA (N = 16)	0	0	0	0	0	0
Normal control (N = 16)	0	0	3/16	1/16	1/16	0
PANS (N = 18)	0	0	3/18	0	0	2/18

^aOne subject was diagnosed with psoriasis and another subject was diagnosed with anti-phospholipid syndrome.
^bAll subjects diagnosed with antibody deficiency syndrome were on IVIG treatment at the time of sample obtainment. All the subjects were shown to have severely impaired responses to Pneumovax’.
^c Abbreviations used; Ab, antibody; ASD, autism spectrum disorder; ASD-IS, ASD-inflammatory subtype; NFA, non-IgE mediated food allergy; PANS, pediatric acute onset neuropsychiatric syndrome.

ISSN: 1742-2094