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Table 1 Levels of the measured parameters in plasma of autistic patients compared to control

From: GABAergic/glutamatergic imbalance relative to excessive neuroinflammation in autism spectrum disorders

Parameter Group N Mean ± SD Percent change P-value
GABA (μmol/l) Control 19 0.53 ± 0.05 100.00 0.001
Autistic 20 0.83 ± 0.12 157.71
Glutamate (μmol/l) Control 19 111.91 ± 4.63 100.00 0.001
Autistic 20 152.80 ± 6.47 136.54
Glutamate/GABA ratio Control 19 214.72 ± 22.26 100.00 0.003
Autistic 20 188.12 ± 30.11 87.61
IL-6 Control 19 363.49 ± 22.88 100.00 0.001
Autistic 20 273.87 ± 32.49 75.34
TNF-α Control 19 346.23 ± 24.95 100.00 0.001
Autistic 20 252.35 ± 63.60 72.89
INF-γ (ng/ml) Control 19 50.85 ± 5.71 100.00 0.001
Autistic 20 85.33 ± 9.06 167.80
IFI16 (ng/ml) Control 19 1.91 ± 0.60 100.00 0.001
Autistic 20 3.11 ± 1.01 162.49
  1. Table 1 describes the independent samples t-test between the control and autistic groups for all parameters.