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Table 2 Receiver operating characteristics (ROC) curve of all parameters in autistic groups

From: GABAergic/glutamatergic imbalance relative to excessive neuroinflammation in autism spectrum disorders

 

Area under the curve

Best cutoff value

Sensitivity %

Specificity %

GABA (μmol/l)

1.000

0.617

100.0%

100.0%

Glutamate (μmol/l)

1.000

131.110

100.0%

100.0%

Glutamate/GABA ratio

0.787

191.792

75.0%

84.2%

IL-6

0.984

333.840

95.0%

94.7%

TNF-α

0.903

285.530

80.0%

100.0%

INF-γ (ng/ml)

1.000

62.780

100.0%

100.0%

IFI16 (ng/ml)

0.864

1.860

100.0%

63.2%