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Table 2 Receiver operating characteristics (ROC) curve of all parameters in autistic groups

From: GABAergic/glutamatergic imbalance relative to excessive neuroinflammation in autism spectrum disorders

  Area under the curve Best cutoff value Sensitivity % Specificity %
GABA (μmol/l) 1.000 0.617 100.0% 100.0%
Glutamate (μmol/l) 1.000 131.110 100.0% 100.0%
Glutamate/GABA ratio 0.787 191.792 75.0% 84.2%
IL-6 0.984 333.840 95.0% 94.7%
TNF-α 0.903 285.530 80.0% 100.0%
INF-γ (ng/ml) 1.000 62.780 100.0% 100.0%
IFI16 (ng/ml) 0.864 1.860 100.0% 63.2%